D E P A R T M E N T S:

EDITORS' REPORT:

EDITORS' REPORT, 2003

Mark Herzberg
J Dent Res 2004 83: 4-5. [Full Text] [PDF]  

DISCOVERY!:

Biomineralization: On the Trail of the Phosphate. Part II: Phosphophoryn, the DMPs, and More

Arthur Veis
In this, the second of a two-part series, the author describes his work on the Dentin Matrix Protein.

J Dent Res 2004 83: 6-10. [Full Text] [PDF]  

CONCISE REVIEWS:

Death in the Life of a Tooth

E. Matalova, A.S. Tucker, and P.T. Sharpe
The authors highlight areas where apoptosis may play key roles in odontogenesis.

J Dent Res 2004 83: 11-16. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

The Induction of Gene Mutations and Micronuclei by Oxiranes and Siloranes in Mammalian Cells in vitro

H. Schweikl, G. Schmalz, and W. Weinmann
The authors estimate, for the first time, the mutagenic activities of various newly synthesized oxiranes and siloranes in mammalian cells.

J Dent Res 2004 83: 17-21. [Abstract] [Full Text] [Figures Only] [PDF]  

Salivary Esterase Activity and Its Association with the Biodegradation of Dental Composites

Y. Finer and J.P. Santerre
Pseudocholinesterase and cholesterol esterase are suitable models for salivary esterase activity which can catalyze the hydrolysis of composite resins in the oral cavity.

J Dent Res 2004 83: 22-26. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

Mesenchymal Stem Cells Acquire Characteristics of Cells in the Periodontal Ligament in vitro

P.R. Kramer, S. Nares, S.F. Kramer, D. Grogan, and M. Kaiser
It may be feasible to use mesenchymal stem cells in clinical applications for repairing and/or regenerating periodontal tissue.

J Dent Res 2004 83: 27-34. [Abstract] [Full Text] [Figures Only] [PDF]  

Mouse Cellular Cementum is Highly Dependent on Growth Hormone Status

J.R. Smid, J.E. Rowland, W.G. Young, T.J. Daley, K.T. Coschigano, J.J. Kopchick, and M.J. Waters
Cellular cementum is a highly responsive growth hormone tissue which may have therapeutic applications in regeneration of the periodontium.

J Dent Res 2004 83: 35-39. [Abstract] [Full Text] [Figures Only] [PDF]  

Effects of TGF-ß on Hyaluronan Anabolism in Fibroblasts Derived from the Synovial Membrane of the Rabbit Temporomandibular Joint

K. Tanimoto, A. Suzuki, S. Ohno, K. Honda, N. Tanaka, T. Doi, K. Yoneno, M. Ohno-Nakahara, Y. Nakatani, M. Ueki, and K. Tanne
TGF-ß1 enhances the expression of hyaluronan (HA) synthase mRNA in TMJ synovial membrane fibroblasts and may contribute to the accumulation of the high-molecular-weight HA needed for the maintenance of viscoelasticity and lubrication of synovial fluid.

J Dent Res 2004 83: 40-44. [Abstract] [Full Text] [Figures Only] [PDF]  

Genetic Analysis of Crown Size in the First Molars Using SMXA Recombinant Inbred Mouse Strains

T. Shimizu, H. Oikawa, J. Han, E. Kurose, and T. Maeda
Tooth crown size is controlled by multiple genes, and there is some independence of genetic control between M¹ and M₁.

J Dent Res 2004 83: 45-49. [Abstract] [Full Text] [Figures Only] [PDF]  

c-fos Expression in Rat Brain Nuclei Following Incisor Tooth Movement

C.M. Magdalena, V.P. Navarro, D.M. Park, M.B.S. Stuani, and M.J.A. Rocha
There is a recruitment of neurons related to nociception and to anti-nociception when tooth movement is increased.

J Dent Res 2004 83: 50-54. [Abstract] [Full Text] [Figures Only] [PDF]  

Variation in Daily Masticatory Muscle Activity in the Rabbit

G.E.J. Langenbach, T. van Wessel, P. Brugman, and T.M.G.J. van Eijden
This is the first report of the use of a lightweight, fully implantable transmitter to study masseter adaptations related to muscle activity patterns in the rabbit.

J Dent Res 2004 83: 55-59. [Abstract] [Full Text] [Figures Only] [PDF]  

Identification of in vivo Pellicle Constituents by Analysis of Serum Immune Responses

J. Li, E.J. Helmerhorst, R.F. Troxler, and F.G. Oppenheim
The polyclonal antibody approach in mice provides a powerful method for identifying various human pellicle proteins, including some showing mineral homeostasis or antimicrobial activity.

J Dent Res 2004 83: 60-64. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Non-primate Lentiviral Vector Administration in the TMJ

S. Kyrkanides, P. Kambylafkas, J.H. Miller, and R.H. Tallents
Lentiviral vectors can potentially serve as a platform for the transfer of anti-nociceptive genes for the management of TMJ pain.

J Dent Res 2004 83: 65-70. [Abstract] [Full Text] [Figures Only] [PDF]  

In situ Effect of Frequent Sucrose Exposure on Enamel Demineralization and on Plaque Composition after APF Application and F Dentifrice Use

A.F. Paes Leme, R. Dalcico, C.P.M. Tabchoury, A.A. Del Bel Cury, P.L. Rosalen, and J.A. Cury
The combination of a single application of APF gel and the daily use of a fluoridated dentifrice neither decreases enamel demineralization nor changes dental plaque composition in comparison with the use of either the APF application or the dentifrice alone.

J Dent Res 2004 83: 71-75. [Abstract] [Full Text] [PDF]  

Is Fluoride Concentration in Dentin and Enamel a Good Indicator of Dental Fluorosis?

A.P.G.F. Vieira, R. Hancock, H. Limeback, R. Maia, and M.D. Grynpas
The authors show, for the first time, a positive correlation between fluoride concentration in dentin and the severity of dental fluorosis.

J Dent Res 2004 83: 76-80. [Abstract] [Full Text] [Figures Only] [PDF]  

Study on the Organoleptic Intensity Scale for Measuring Oral Malodor

J. Greenman, J. Duffield, P. Spencer, M. Rosenberg, D. Corry, S. Saad, P. Lenton, G. Majerus, S. Nachnani, and M. El-Maaytah
The authors demonstrate the exponential nature of the olfactory response and show that any single compound’s contribution to malodor depends on odor power and threshold in addition to concentration.

J Dent Res 2004 83: 81-85. [Abstract] [Full Text] [Figures Only] [PDF]  

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