D E P A R T M E N T S:

EDITORIAL:

Time to Think

Anthony J. (Tony) Smith
J Dent Res 2004 83: 743. [Full Text] [PDF]  

WORKSHOP REPORT:

Methods for Enhancing the Efficiency of Dental/Oral Health Clinical Trials: Current Status, Future Possibilities

M.L. Barnett and B.L. Pihlstrom
This summarizes a workshop that considered a variety of ways in which technological insights can be applied to clinical trials to enhance their efficiency and cost-effectiveness.

J Dent Res 2004 83: 744-750. [Abstract] [Full Text] [PDF]  

RAPID COMMUNICATION:

Tissue-engineered Rabbit Cranial Suture from Autologous Fibroblasts and BMP2

L. Hong and J.J. Mao
This is the first report of de novo formation of tissue-engineered cranial suture from autologous cells.

J Dent Res 2004 83: 751-756. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Clinical:

Cortical Activation Resulting from Painless Vibrotactile Dental Stimulation Measured by Functional Magnetic Resonance Imaging (fMRI)

D.A. Ettlin, H. Zhang, K. Lutz, T. Järmann, D. Meier, L.M. Gallo, L. Jäncke, and S. Palla
The authors confirm the value of non-invasive functional MRI methodology in functional brain studies related to dental stimulation.

J Dent Res 2004 83: 757-761. [Abstract] [Full Text] [Figures Only] [PDF]  

Chewing-side Preference is Involved in Differential Cortical Activation Patterns during Tongue Movements after Bilateral Gum-chewing: a Functional Magnetic Resonance Imaging Study

H. Shinagawa, T. Ono, E. Honda, T. Sasaki, M. Taira, A. Iriki, T. Kuroda, and K. Ohyama
Bilateral gum-chewing enhances activation of the primary sensorimotor cortex ipsilateral to chewing-side preference during tongue movements.

J Dent Res 2004 83: 762-766. [Abstract] [Full Text] [Figures Only] [PDF]  

The Highly Leukotoxic JP2 Clone of Actinobacillus actinomycetemcomitans and Progression of Periodontal Attachment Loss

D. Haubek, O.-K. Ennibi, K. Poulsen, N. Benzarti, and V. Baelum
This is the first population-based study to demonstrate that the presence of the JP2 clone of A. actinomycetemcomitans results in an increased risk of progression of clinical attachment loss.

J Dent Res 2004 83: 767-770. [Abstract] [Full Text] [Figures Only] [PDF]  

Root Lengths in 47,XYY Males’ Permanent Teeth

R. Lähdesmäki and L. Alvesalo
Excess root dentin growth in 47,XYY males, as well as sexual dimorphism in the growth of crown and root dentin, might be caused by the same factor on the Y chromosome.

J Dent Res 2004 83: 771-775. [Abstract] [Full Text] [PDF]  

Modeling Multivariate Binary Responses with Multiple Levels of Nesting Based on Alternating Logistic Regressions: an Application to Caries Aggregation

C.V. Ananth and M.L. Kantor
Alternating logistic regressions is a convenient and useful technique for explicit modeling of the dependence structure between pairs of responses and is applicable to dental research problems involving clustered or nested responses.

J Dent Res 2004 83: 776-781. [Abstract] [Full Text] [Figures Only] [PDF]  

Linkage Disequilibrium between MSX1 and Non-syndromic Cleft Lip/Palate in the Chilean Population

J. Suazo, J.L. Santos, H. Carreño, L. Jara, and R. Blanco
The authors’ findings support the hypothesis of the contribution of MSX1 in the etiology of non-syndromic cleft lip/palate in the Chilean population.

J Dent Res 2004 83: 782-785. [Abstract] [Full Text] [PDF]  

Biological:

Oral Epithelial Overexpression of IL-1 Causes Periodontal Disease

S. Dayan, P. Stashenko, R. Niederman, and T.S. Kupper
Elevated levels of IL-1 in the oral micro-environment can mediate all of the clinical features of periodontal disease.

J Dent Res 2004 83: 786-790. [Abstract] [Full Text] [Figures Only] [PDF]  

IL-1 Stimulates Cathepsin K Expression in Osteoclasts via the Tyrosine Kinase-NF-B Pathway

S. Kamolmatyakul, W. Chen, S. Yang, Y. Abe, R. Moroi, A.M. Ashique, and Y.-P. Li
IL-1 up-regulates cathepsin K gene expression at the transcription level, possibly via the tyrosine-kinase-NF-B pathway.

J Dent Res 2004 83: 791-796. [Abstract] [Full Text] [Figures Only] [PDF]  

Deficient Cell Proliferation in Palatal Shelf Mesenchyme of CL/Fr Mouse Embryos

Y. Sasaki, S. Tanaka, T. Hamachi, and Y. Taya
A cleft palate follows reduced cell proliferation of secondary palate mesenchyme in CL/Fr mice.

J Dent Res 2004 83: 797-801. [Abstract] [Full Text] [Figures Only] [PDF]  

In situ Biofilm Formation by Multi-species Oral Bacteria Under Flowing and Anaerobic Conditions

S.K. Filoche, M. Zhu, and C.D. Wu
The viability of the base film may not be essential in biofilm re-establishment, and bacterial aggregation states appear to affect antimicrobial susceptibility.

J Dent Res 2004 83: 802-806. [Abstract] [Full Text] [Figures Only] [PDF]  

Biomaterials & Bioengineering:

Collagen Cross-linking and Ultimate Tensile Strength in Dentin

P.A. Miguez, P.N.R. Pereira, P. Atsawasuwan, and M. Yamauchi
The profile of collagen cross-linking varies as a function of anatomical location in dentin, and the difference may partly explain site-specific tensile strength.

J Dent Res 2004 83: 807-810. [Abstract] [Full Text] [Figures Only] [PDF]  

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