D E P A R T M E N T S:

GUEST EDITORIAL:

Dental, Oral, and Craniofacial Research: the View from the NIDCR

Lawrence A. Tabak
J Dent Res 2004 83: 196-197. [Full Text] [PDF]  

LETTER TO THE EDITOR:

Epigenetic Modulation for Reparative Dentinogenesis?

L. Tremolizzo, A. Senna, and V. Rodriguez-Menendez
J Dent Res 2004 83: 198. [Full Text] [PDF]  

RAPID COMMUNICATION:

RNA Profiling of Cell-free Saliva Using Microarray Technology

Y. Li, X. Zhou, M.A.R. St. John, and D.T.W. Wong
This is the first report where human mRNA in unstimulated saliva is globally profiled.

J Dent Res 2004 83: 199-203. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Bone Regeneration via a Mineral Substrate and Induced Angiogenesis

W.L. Murphy, C.A. Simmons, D. Kaigler, and D.J. Mooney
Induced angiogenesis can enhance tissue regeneration, supporting the concept of therapeutic angiogenesis in tissue-engineering strategies

J Dent Res 2004 83: 204-210. [Abstract] [Full Text] [Figures Only] [PDF]  

On the in vitro Fatigue Behavior of Human Dentin: Effect of Mean Stress

R.K. Nalla, J.H. Kinney, S.J. Marshall, and R.O. Ritchie
The authors present the first fatigue data for human dentin under tension and compression loading.

J Dent Res 2004 83: 211-215. [Abstract] [Full Text] [Figures Only] [PDF]  

Collagen Degradation by Host-derived Enzymes during Aging

D.H. Pashley, F.R. Tay, C. Yiu, M. Hashimoto, L. Breschi, R.M. Carvalho, and S. Ito
Collagen degradation occurs over time via host-derived matrix metalloproteinase that are released slowly over time.

J Dent Res 2004 83: 216-221. [Abstract] [Full Text] [Figures Only] [PDF]  

In vitro Estrogenicity of Resin Composites

H. Wada, H. Tarumi, S. Imazato, M. Narimatsu, and S. Ebisu
The observed estrogenic activity of 6 composites is associated with the elution of either HMBP or DMPA.

J Dent Res 2004 83: 222-226. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Mental Stress-induced Physiological Changes in the Human Masseter Muscle

O. Hidaka, M. Yanagi, and K. Takada
This is the first evaluation of the effect of mental stress on the autonomic nervous system.

J Dent Res 2004 83: 227-231. [Abstract] [Full Text] [Figures Only] [PDF]  

Persistent Colonization with Tannerella forsythensis and Loss of Attachment in Adolescents

S. Hamlet, R. Ellwood, M. Cullinan, H. Worthington, J. Palmer, P. Bird, D. Narayanan, R. Davies, and G. Seymour
T. forsythensis is strongly associated with the loss of attachement in an adolescent population.

J Dent Res 2004 83: 232-235. [Abstract] [Full Text] [Figures Only] [PDF]  

Speech with Maxillary Implant Prostheses: Ratings of Articulation

G. Heydecke, D.H. McFarland, J.S. Feine, and J.P. Lund
Maxillary implant overdentures with and without palates enable patients to produce more intelligible speech than fixed prostheses.

J Dent Res 2004 83: 236-240. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

Opg, Rank, and Rankl in Tooth Development: Co-ordination of Odontogenesis and Osteogenesis

A. Ohazama, J.-M. Courtney, and P.T. Sharpe
The spatiotemporal expression of these molecules in early tooth and bone primordia cells has a role in co-ordinating bone and tooth development.

J Dent Res 2004 83: 241-244. [Abstract] [Full Text] [Figures Only] [PDF]  

Gene Expression Profiling of Mouse Condylar Cartilage during Mastication by Means of Laser Microdissection and cDNA Array

J. Watahiki, T. Yamaguchi, T. Irie, H. Nakano, K. Maki, and T. Tachikawa
Gene expression changes during mandibular condylar cartilage growth, and these changes coincide with the initiation of mastication.

J Dent Res 2004 83: 245-249. [Abstract] [Full Text] [Figures Only] [PDF]  

Effects of Sex Hormone Disturbances on Craniofacial Growth in Newborn Mice

T. Fujita, J. Ohtani, M. Shigekawa, T. Kawata, M. Kaku, S. Kohno, K. Tsutsui, K. Tenjo, M. Motokawa, Y. Tohma, and K. Tanne
Craniofacial growth is inhibited by sex hormone disturbances, not only in puberty but also immediately after birth.

J Dent Res 2004 83: 250-254. [Abstract] [Full Text] [Figures Only] [PDF]  

Changed Morphology and Mechanical Properties of Cancellous Bone in the Mandibular Condyles of Edentate People

E.B.W. Giesen, M. Ding, M. Dalstra, and T.M.G.J. van Eijden
Under reduced mechanical load, the fundamental relationship between bone morphology and mechanical properties does not change.

J Dent Res 2004 83: 255-259. [Abstract] [Full Text] [Figures Only] [PDF]  

Prostaglandin E₂ Regulates Interleukin-1ß-induced Matrix Metalloproteinase-3 Production in Human Gingival Fibroblasts

S.M.P.M. Ruwanpura, K. Noguchi, and I. Ishikawa
Different regulation of IL-1ß-induced MMP-3 reduction by PGE₂ between healthy and periodontally diseased tissues may be involved in the pathogenesis of periodontal tissues.

J Dent Res 2004 83: 260-265. [Abstract] [Full Text] [Figures Only] [PDF]  

Construction and Immunogenic Characterization of a Fusion Anti-caries DNA Vaccine against PAc and Glucosyltransferase I of Streptococcus mutans

J.H. Guo, R. Jia, M.W. Fan, Z. Bian, Z. Chen, and B. Peng
This is the first report where a DNA vaccine encoding gene fragments of two virulence factors has been found to result in better protection against dental caries than a vaccine encoding one factor alone.

J Dent Res 2004 83: 266-270. [Abstract] [Full Text] [Figures Only] [PDF]  

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