D E P A R T M E N T S:

GUEST EDITORIAL:

PhD in Dentistry for Clinician-Scientists

Ivar A. Mjör
The author makes a case for establishing programs in North American universities to address the lack of adequately trained clinical faculty.

J Dent Res 2004 83: 662-663. [Full Text] [PDF]  

R E S E A R C H  R E P O R T S:

Biological:

Expression of SIBLINGs and Their Partner MMPs in Salivary Glands

K.U.E. Ogbureke and L.W. Fisher
Expression of all SIBLINGs in normal, non-mineralizing epithelial tissue suggests that they serve at least one function in vivo other than directly promoting matrix mineralization—a function hypothesized to involve local activation of MMPs.

J Dent Res 2004 83: 664-670. [Abstract] [Full Text] [Figures Only] [PDF]  

Apoptotic Effects of LPS on Fibroblasts are Indirectly Mediated through TNFR1

M. Alikhani, Z. Alikhani, and D.T. Graves
LPS inoculation induces apoptotic gene expression through TNFR1.

J Dent Res 2004 83: 671-676. [Abstract] [Full Text] [Figures Only] [PDF]  

Semaphorin Profiling of Periodontal Fibroblasts and Osteoblasts

T.E. Lallier
Differential expression of semaphorins and plexins may be involved in regulating cell-sorting in the formation and regeneration of the periodontal attachment structure.

J Dent Res 2004 83: 677-682. [Abstract] [Full Text] [Figures Only] [PDF]  

Effects of Cyclosporin-A-induced Immunosuppression on Periapical Lesions in Rats

T. Kawahara, S. Murakami, Y. Noiri, A. Ehara, N. Takemura, S. Furukawa, and S. Ebisu
Cyclosporin A inhibits periapical destruction by interfering with T-cell function in periapical lesions.

J Dent Res 2004 83: 683-687. [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Properties of the Hertwig’s Epithelial Root Sheath in Mice

H. Yamamoto, S.-W. Cho, E.-J. Kim, J.-Y. Kim, N. Fujiwara, and H.-S. Jung
The authors present a comprehensive model describing the morphogenesis of early root development in vertebrates.

J Dent Res 2004 83: 688-692. [Abstract] [Full Text] [Figures Only] [PDF]  

Influence of Temporomandibular Joint Pain on Sleep Patterns: Role of Nitric Oxide

T.C.B. Schütz, M.L. Andersen, and S. Tufik
The inhibitor of nitric oxide synthase (L-NAME) improved sleep efficiency, suggesting the involvement of nitric oxide in painful temporomandibular joint conditions.

J Dent Res 2004 83: 693-697. [Abstract] [Full Text] [Figures Only] [PDF]  

Biomaterials & Bioengineering:

Amelogenin-guided Crystal Growth on Fluoroapatite Glass-ceramics

S. Habelitz, A. Kullar, S.J. Marshall, P.K. DenBesten, M. Balooch, G.W. Marshall, and W. Li
Amelogenin proteins control the direction and rate of growth of apatite in vitro.

J Dent Res 2004 83: 698-702. [Abstract] [Full Text] [Figures Only] [PDF]  

Inhibition of Phosphatidylinositol 3-Kinase Amplifies TEGDMA-induced Apoptosis in Primary Human Pulp Cells

G. Spagnuolo, K. Galler, G. Schmalz, C. Cosentino, S. Rengo, and H. Schweikl
Depression of P13K signaling may be a primary target in TEGDMA-induced apoptosis.

J Dent Res 2004 83: 703-707. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Masticatory Function with Implant-supported Overdentures

F.M.C. van Kampen, A. van der Bilt, M.S. Cune, F.A. Fontijn-Tekamp, and F. Bosman
Significantly better masticatory performance, combined with a slightly smaller number of chewing cycles after implant treatment, results in smaller food particles being swallowed.

J Dent Res 2004 83: 708-711. [Abstract] [Full Text] [Figures Only] [PDF]  

Predictors of Outcome for Orofacial Pain in the General Population: a Four-year Follow-up Study

T.V. Macfarlane, A.S. Blinkhorn, R.M. Davies, J. Kincey, and H.V. Worthington
The authors identify factors that predict the persistence of pain.

J Dent Res 2004 83: 712-717. [Abstract] [Full Text] [PDF]  

Mouth-opening Increases Upper-airway Collapsibility without Changing Resistance during Midazolam Sedation

T. Ayuse, T. Inazawa, S. Kurata, I. Okayasu, E. Sakamoto, K. Oi, H. Schneider, and A.R. Schwartz
Maximal mouth-opening increases upper-airway collapsibility, which contributes to upper-airway obstruction at atmosphere during midazolam sedation.

J Dent Res 2004 83: 718-722. [Abstract] [Full Text] [Figures Only] [PDF]  

MSX1, PAX9, and TGFA Contribute to Tooth Agenesis in Humans

A.R. Vieira, R. Meira, A. Modesto, and J.C. Murray
This is the first report to investigate the possible association between human tooth agenesis and TGFA.

J Dent Res 2004 83: 723-727. [Abstract] [Full Text] [PDF] [Appendix]  

Modulation of Clinical Expression of Plaque-induced Gingivitis: Effect of Incisor Crown Form

L. Trombelli, R. Farina, R. Manfrini, and D.N. Tatakis
Incisor crown form appears to affect the bleeding response of inflamed gingival tissues, while it does not influence an individual’s susceptibility to plaque-induced gingivitis.

J Dent Res 2004 83: 728-731. [Abstract] [Full Text] [PDF]  

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