D E P A R T M E N T S:

GUEST EDITORIAL:

The Neglected Global Burden of Chronic Oral Diseases

M.D. Mignogna and S. Fedele
J Dent Res 2006 85: 390-391. [Full Text] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Porphyromonas gingivalis-Epithelial Cell Interactions in Periodontitis

E. Andrian, D. Grenier, and M. Rouabhia
The authors review current knowledge on the molecular cross-talk between P. gingivalis and gingival epithelial cells in the development of periodontitis.

J Dent Res 2006 85: 392-403. [Abstract] [Full Text] [Figures Only] [PDF]  

Osteopontin and Mucosal Protection

J. Sodek, A. Paes Batista Da Silva, and R. Zohar
This review summarizes current knowledge of the biological activities of osteopontin involved in the development of inflammatory responses and in wound healing, and indicates how these activities may affect the protection of mucosal tissues.

J Dent Res 2006 85: 404-415. [Abstract] [Full Text] [Figures Only] [PDF]  

RAPID COMMUNICATION:

Bone Marrow Cells Can Give Rise to Ameloblast-like Cells

B. Hu, F. Unda, S. Bopp-Kuchler, L. Jimenez, X.J. Wang, Y. Haïkel, S.L. Wang, and H. Lesot
The authors show for the first time that bone-marrow-derived cells can be reprogrammed to give rise to ameloblast-like cells, offering novel possibilities for tooth-tissue engineering.

J Dent Res 2006 85: 416-421. [Abstract] [Full Text] [Figures Only] [PDF] Appendix  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Hydrolysis of Functional Monomers in a Single-bottle Self-etching Primer—Correlation of ¹³C NMR and TEM Findings

N. Nishiyama, F.R. Tay, K. Fujita, D.H. Pashley, K. Ikemura, N. Hiraishi, and N.M. King
Hydrolysis of functional methacrylate monomoers occurs despite intermittent refrigeration.

J Dent Res 2006 85: 422-426. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

Sonic Hedgehog Signaling is Important in Tooth Root Development

M. Nakatomi, I. Morita, K. Eto, and M.S. Ota
Shh signaling is important in tooth root development.

J Dent Res 2006 85: 427-431. [Abstract] [Full Text] [Figures Only] [PDF]  

Responses of Rat Pulp Cells to Heat Stress in vitro

T. Amano, T. Muramatsu, K. Amemiya, K. Kubo, and M. Shimono
Dental pulp possesses protective factors, including heat-shock proteins, and recovers viability of intercellular communication and alkaline phosphatase activity after heat stress.

J Dent Res 2006 85: 432-435. [Abstract] [Full Text] [Figures Only] [PDF]  

Activation of iCaspase-9 in Neovessels Inhibits Oral Tumor Progression

M.S. Pinsky, W. Song, Z. Dong, K. Warner, B. Zeitlin, E. Karl, D.E. Hall, and J.E. Nör
The authors demonstrate for the first time that the activation of iCaspase-9 in endothelial cells is sufficient to mediate a decrease in tumor neovascularization.

J Dent Res 2006 85: 436-441. [Abstract] [Full Text] [Figures Only] [PDF]  

Edema in Oral Mucosa after LPS or Cytokine Exposure

A. Bletsa, T. Nedrebø, K.J. Heyeraas, and E. Berggreen
Lipopolysaccharide, interleukin-1ß, and tumor necrosis factor- induce lowering of interstitial fluid pressure in the rat oral mucosa and contribute to edema formation in LPS-induced gingivitis.

J Dent Res 2006 85: 442-446. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Regulation of PLAP-1 Expression in Periodontal Ligament Cells

S. Yamada, Y. Ozawa, M. Tomoeda, R. Matoba, K. Matsubara, and S. Murakami
Periodontal-ligament-associated protein-1 expression may be closely associated with the process of cytodifferentiation of periodontal ligament cells into mineralized-tissue-forming cells.

J Dent Res 2006 85: 447-451. [Abstract] [Full Text] [Figures Only] [PDF]  

Accumulation of Non-steroidal Anti-inflammatory Drugs by Gingival Fibroblasts

M.M. Zavarella, O. Gbemi, and J.D. Walters
There is no evidence that gingival fibroblasts contribute to elevated non-steroidal anti-inflammatory drug levels in healthy gingiva.

J Dent Res 2006 85: 452-456. [Abstract] [Full Text] [Figures Only] [PDF]  

Cyclical Tensile Force on Periodontal Ligament Cells Inhibits Osteoclastogenesis through OPG Induction

H. Kanzaki, M. Chiba, A. Sato, A. Miyagawa, K. Arai, S. Nukatsuka, and H. Mitani
Tensile force inhibits the osteoclastogenesis-supporting activity of periodontal ligament cells by inducing the up-regulation of osteoprotegerin via transforming growth factor-beta stimulation.

J Dent Res 2006 85: 457-462. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Nutrition Counseling Increases Fruit and Vegetable Intake in the Edentulous

J. Bradbury, J.M. Thomason, N.J.A. Jepson, A.W.G. Walls, P.F. Allen, and P.J. Moynihan
This is the first published controlled study to have investigated the effect of dietary intervention contemporaneous with dental intervention on positive change in dietary behavior.

J Dent Res 2006 85: 463-468. [Abstract] [Full Text] [Figures Only] [PDF]  

Caries-inhibiting Effect of Chlorhexidine Varnish in Pits and Fissures

Q. Zhang, M.A. van ‘t Hof, G.J. Truin, E.M. Bronkhorst, and W.H. van Palenstein Helderman
The application of chlorhexidine varnish to the pits and fissures of permanent first molars in six- to seven-year-old children has a short-term caries-inhibiting effect, but its efficiency is questionable in a child population with a low caries incidence.

J Dent Res 2006 85: 469-472. [Abstract] [Full Text] [PDF]  

Peri-implant Inflammation Defined by the Implant-Abutment Interface

N. Broggini, L.M. McManus, J.S. Hermann, R. Medina, R.K. Schenk, D. Buser, and D.L. Cochran
The implant-abutment interface dictates the intensity and location of peri-implant inflammatory cell accumulation, a potential contributing component in the extent of implant-associated alveolar bone loss.

J Dent Res 2006 85: 473-478. [Abstract] [Full Text] [Figures Only] [PDF]  

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