D E P A R T M E N T S:

DISCOVERY!:

Taking up Challenges at the Interface of Wear and Tear

Frank Lobbezoo
The author reflects on the central position of oral movement disorders, such as bruxism, in the discipline of oral kinesiology.

J Dent Res 2007 86: 101-103. [Full Text] [Figures Only] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

The Epidemiology and Risk Factors of Head and Neck Cancer: a Focus on Human Papillomavirus

C.C.R. Ragin, F. Modugno, and S.M. Gollin
The authors present their current understanding of the relationship between human papillomavirus (HPV) and head and neck squamous cell carcinoma, and describe future research directions that may lead to a better understanding of the involvement of HPV in head and neck cancer.

J Dent Res 2007 86: 104-114. [Abstract] [Full Text] [Figures Only] [PDF]  

Tissue-engineered Oral Mucosa: a Review of the Scientific Literature

K. Moharamzadeh, I.M. Brook, R. Van Noort, A.M. Scutt, and M.H. Thornhill
The authors review different tissue-engineering strategies used for the production of human oral mucosal composites, their relative advantages and drawbacks, and their applications.

J Dent Res 2007 86: 115-124. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Clinical:

Probiotics Reduce the Prevalence of Oral Candida in the Elderly—a Randomized Controlled Trial

K. Hatakka, A.J. Ahola, H. Yli-Knuuttila, M. Richardson, T. Poussa, J.H. Meurman, and R. Korpela
Probiotic bacteria can be effective in controlling oral Candida and hyposalivation in the elderly.

J Dent Res 2007 86: 125-130. [Abstract] [Full Text] [Figures Only] [PDF]  

Secular Trends in Socio-economic Disparities in Edentulism: USA, 1972–2001

J. Cunha-Cruz, P.P. Hujoel, and P. Nadanovsky
The absolute prevalence differences in edentulism between low and high socio-economic positions have remained unchanged over the last three decades.

J Dent Res 2007 86: 131-136. [Abstract] [Full Text] [PDF]  

Unilateral Posterior Crossbite is Not Associated with TMJ Clicking in Young Adolescents

M. Farella, A. Michelotti, G. Iodice, S. Milani, and R. Martina
Posterior unilateral crossbite does not appear to be a risk factor for temporomandibular joint clicking, at least in young adolescents.

J Dent Res 2007 86: 137-141. [Abstract] [Full Text] [PDF]  

Biomaterials & Bioengineering:

Fracture of Porcelain-veneered Structures in Fatigue

B. Kim, Y. Zhang, M. Pines, and V.P. Thompson
The stronger Y-TZP cores had better resistance to bulk fracture than did their alumina counterparts.

J Dent Res 2007 86: 142-146. [Abstract] [Full Text] [Figures Only] [PDF]  

A Role for Proteoglycans in Mineralized Tissue-Titanium Adhesion

H.K. Nakamura, F. Butz, L. Saruwatari, and T. Ogawa
The authors suggest a role for proteoglycan/glycosaminoglycan complexes in the establishment of tissue-titanium adhesion.

J Dent Res 2007 86: 147-152. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biological:

Processing of Ameloblastin by MMP-20

T. Iwata, Y. Yamakoshi, J.C.-C. Hu, I. Ishikawa, J.D. Bartlett, P.H. Krebsbach, and J.P. Simmer
MMP-20 processes ameloblastin in vitro and in vivo.

J Dent Res 2007 86: 153-157. [Abstract] [Full Text] [Figures Only] [PDF]  

Phex Mutation Causes the Reduction of Npt2b mRNA in Teeth

T. Onishi, R. Okawa, T. Ogawa, S. Shintani, and T. Ooshima
The loss of Phex function is related to the defect of Npt2b expression in teeth, and Npt2b reduction is an intrinsic defect of Hyp mouse teeth.

J Dent Res 2007 86: 158-162. [Abstract] [Full Text] [Figures Only] [PDF]  

Nitric Oxide in Pulp Cell Growth, Differentiation, and Mineralization

R. Yasuhara, T. Suzawa, Y. Miyamoto, X. Wang, M. Takami, A. Yamada, and R. Kamijo
This is the first report on the role of nitric oxide in pulp cell differentiation.

J Dent Res 2007 86: 163-168. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Bacterial Infection Promotes DNA Hypermethylation

Y.A. Bobetsis, S.P. Barros, D.M. Lin, J.R. Weidman, D.C. Dolinoy, R.L. Jirtle, K.A. Boggess, J.D. Beck, and S. Offenbacher
This is the first report that infection can lead to host epigenetic modification of an imprinted gene.

J Dent Res 2007 86: 169-174. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Human Cytomegalovirus Enhances A. actinomycetemcomitans Adherence to Cells

W. Teughels, I. Sliepen, M. Quirynen, S. Kinder Haake, J. Van Eldere, P. Fives-Taylor, and M. Van Ranst
Adherence of Actinobacillus actinomycetemcomitans is influenced by human cytomegalovirus in vitro.

J Dent Res 2007 86: 175-180. [Abstract] [Full Text] [Figures Only] [PDF]  

P2X4 is Up-regulated in Gingival Fibroblasts after Periodontal Surgery

I. Binderman, H. Bahar, J. Jacob-Hirsch, S. Zeligson, N. Amariglio, G. Rechavi, S. Shoham, and A. Yaffe
The authors are the first to identify the P2X4 ligand-gated ion channel purinoreceptor in the membranes of marginal gingival cells at some distance from bone.

J Dent Res 2007 86: 181-185. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Signaling Pathways Regulating IL-1-induced COX-2 Expression

S. Ogata, Y. Kubota, T. Yamashiro, H. Takeuchi, T. Ninomiya, Y. Suyama, and K. Shirasuna
In odontogenic keratocyst fibroblasts, IL-1 may stimulate COX-2 expression both through the PKC-dependent activation of ERK1/2, p38, and JNK signaling pathways, and through the NF-B cascade.

J Dent Res 2007 86: 186-191. [Abstract] [Full Text] [Figures Only] [PDF]  

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