D E P A R T M E N T S:

DISCOVERY!:

Biomechanics of the Temporomandibular Joint

E. Tanaka and J.H. Koolstra
The authors write in honor of the late Theo van Eijden for his contributions to our understanding of the biomechanics of the human masticatory system.

J Dent Res 2008 87: 989-991. [Full Text] [Figures Only] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

siRNA, miRNA, and shRNA: in vivo Applications

P.N. Pushparaj, J.J. Aarthi, J. Manikandan, and S.D. Kumar
The authors analyze research findings relative to in vivo applications of siRNAs, miRNAs, and shRNAs.

J Dent Res 2008 87: 992-1003. [Abstract] [Full Text] [Figures Only] [PDF]  

Tools for Interpreting Large-scale Protein Profiling in Microbiology

E.L. Hendrickson, R.J. Lamont, and M. Hackett
The authors provide a critical introduction to the types of data analysis tools available for exploring proteomics data from microbial species.

J Dent Res 2008 87: 1004-1015. [Abstract] [Full Text] [Figures Only] [PDF] Appendix  

RAPID COMMUNICATION:

Pyrosequencing analysis of the Oral Microflora of healthy adults

B.J.F. Keijser, E. Zaura, S.M. Huse, J.M.B.M. van der Vossen, F.H.J. Schuren, R.C. Montijn, J.M. ten Cate, and W. Crielaard
The authors give a radically new insight into the diversity of human oral microflora, which, with an estimated number of 19,000 phylotypes, is considerably higher than previously reported.

J Dent Res 2008 87: 1016-1020. [Abstract] [Full Text] [Figures Only] [PDF] Appendix  

DEPARTMENTS:

STATEMENT OF OWNERSHIP

J Dent Res 2008 87: 1080. [Full Text] [PDF]  

R E S E A R C H  R E P O R T S:

Clinical:

Novel Mutations in GJA1 Cause Oculodentodigital syndrome

A. Fenwick, R.J. Richardson, J. Butterworth, M.J. Barron, and M.J. Dixon
The authors report 8 missense mutations in the coding region of GJA1, 6 of which have not been described previously, in ten unrelated families diagnosed with oculodentodigital syndrome.

J Dent Res 2008 87: 1021-1026. [Abstract] [Full Text] [Figures Only] [PDF]  

Tricho-Rhino-Phalangeal Syndrome with Supernumerary Teeth

P. Kantaputra, I. Miletich, H.-J. Lüdecke, E.Y. Suzuki, V. Praphanphoj, R. Shivdasani, M. Wuelling, A. Vortkamp, D. Napierala, and P.T. Sharpe
The authors suggest a role for TRPS1 in tooth morphogenesis.

J Dent Res 2008 87: 1027-1031. [Abstract] [Full Text] [Figures Only] [PDF]  

Fluoride Release from CaF₂ and Enamel Demineralization

L.M.A. Tenuta, R.V. Cerezetti, A.A. Del Bel Cury, C.P.M. Tabchoury, and J.A. Cury
F released to plaque fluid from CaF₂ formed on enamel may play a significant role in the anticaries effect of professionally applied F agents.

J Dent Res 2008 87: 1032-1036. [Abstract] [Full Text] [Figures Only] [PDF]  

Direct and Indirect Effects of Interdental Hygiene in a Clinical Trial

Y.-K. Tu, M. Jackson, M. Kellett, and V. Clerehugh
Improved oral hygiene performance can reduce gingival inflammation and therefore yield greater pocket reduction and less bleeding on probing.

J Dent Res 2008 87: 1037-1042. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biomaterials & Bioengineering:

Factors Affecting Photopolymerization Stress in Dental Composites

C.S. Pfeifer, J.L. Ferracane, R.L. Sakaguchi, and R.R. Braga
In a comparison of two composites, differences in reaction rate did not correlate with differences in shrinkage.

J Dent Res 2008 87: 1043-1047. [Abstract] [Full Text] [Figures Only] [PDF]  

The Influence of Barrier Membranes on Autologous Bone Grafts

P.F.M. Gielkens, J. Schortinghuis, J.R. de Jong, A.M.J. Paans, J.L. Ruben, G.M. Raghoebar, B. Stegenga, and R.R.M. Bos
The indication of barrier membrane use to prevent bone modeling with resorption, and to enhance the incorporation of autologous onlay bone grafts, is still subject to debate.

J Dent Res 2008 87: 1048-1052. [Abstract] [Full Text] [Figures Only] [PDF]  

Regional Dynamic Tensile Properties of the TMJ Disc

G.R. Snider, J. Lomakin, M. Singh, S.H. Gehrke, and M.S. Detamore
This is the first study to present a multi-regional, multi-directional characterization of the dynamic tensile properties of the TMJ disc.

J Dent Res 2008 87: 1053-1057. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

XBP1 May Determine the Size of the Ameloblast Endoplasmic Reticulum

M. Tsuchiya, C.E. Tye, R. Sharma, C.E. Smith, and J.D. Bartlett
Xbp1 expression correlates positively with percent volume of ameloblast endoplasmic reticulum.

J Dent Res 2008 87: 1058-1062. [Abstract] [Full Text] [Figures Only] [PDF]  

Association between High miR-211 microRNA Expression and the Poor Prognosis of Oral Carcinoma

K.-W. Chang, C.-J. Liu, T.-H. Chu, H.-W. Cheng, P.-S. Hung, W.-Y. Hu, and S.-C. Lin
High miR-211 expression may be associated with the progression of oral carcinoma and poor patient outcomes.

J Dent Res 2008 87: 1063-1068. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Areca-treated Fibroblasts Enhance Tumorigenesis of Oral Epithelial Cells

H.-H. Lu, C.-J. Liu, T.-Y. Liu, S.-Y. Kao, S.-C. Lin, and K.-W. Chang
Areca nut extract may impair oral fibroblasts and modulate the progression of oral epithelial oncogenesis via their secreted molecules.

J Dent Res 2008 87: 1069-1074. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Mechanism of Azithromycin Treatment on Gingival Overgrowth

J.-Y. Kim, S.-H. Park, K.-S. Cho, H.-J. Kim, C.-K. Lee, K.-K. Park, S.-H. Choi, and W.-Y. Chung
This is the first study to explain the mechanism underlying azithromycin therapy on cyclosporine A-induced gingival overgrowth by examining the cellular and molecular effects of azithromycin on cell proliferation and the collagen metabolism modified by cyclosporin A in human gingival fibroblasts.

J Dent Res 2008 87: 1075-1079. [Abstract] [Full Text] [Figures Only] [PDF]  

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