D E P A R T M E N T S:

LETTERS TO THE EDITOR:

Controlled Clinical Trials and Practice-based Research in Dentistry

Richard D. Finkelman, Alan M. Polson, and Ivar A. Mjör
J Dent Res 2008 87: e2. [Full Text] [PDF]  

DISCOVERY!:

25-year Analysis of a Dental Undergraduate Research Training Program (BSc Dent) at the University of Manitoba Faculty of Dentistry

J.E. Scott, J. de Vries, and A.M. Iacopino
The authors present long-term data validating many hypotheses and short-term observations regarding the benefits of dental student research programs.

J Dent Res 2008 87: 1085-1088. [Abstract] [Full Text] [Figures Only] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Dento-Craniofacial Phenotypes and underlying Molecular Mechanisms in Hypohidrotic Ectodermal Dysplasia (HED): a Review

F. Clauss, M.-C. Manière, F. Obry, E. Waltmann, S. Hadj-Rabia, C. Bodemer, Y. Alembik, H. Lesot, and M. Schmittbuhl
The purposes of this review are to state precisely the dentocraniofacial and bone phenotypes associated with hypohidrotic ectodermal dysplasias and to point out molecular mechanisms underlying these anomalies from recent progress in the understanding of the EDA-NF-B pathway.

J Dent Res 2008 87: 1089-1099. [Abstract] [Full Text] [Figures Only] [PDF]  

Orally Based Diagnosis of Celiac Disease: Current Perspectives

L. Pastore, G. Campisi, D. Compilato, and L. Lo Muzio
The authors demonstrate that orally based diagnosis of celiac disease is attractive and promising, although additional evaluations with standardized collection and analysis methods are needed.

J Dent Res 2008 87: 1100-1107. [Abstract] [Full Text] [Figures Only] [PDF]  

RAPID COMMUNICATION:

Overlapping DSPP Mutations Cause Dentin Dysplasia and Dentinogenesis Imperfecta

D.A. McKnight, J.P. Simmer, P.S. Hart, T.C. Hart, and L.W. Fisher
The authors describe a new frameshift mutation showing that overlapping DSPP mutations can give rise to either dentinogenesis imperfecta or dentin dysplasia phenotypes.

J Dent Res 2008 87: 1108-1111. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Improved Resin Infiltration of Natural Caries Lesions

H. Meyer-Lueckel and S. Paris
Resins with higher penetration coefficients (infiltrants) show superior ability to penetrate natural lesions compared with resins with lower penetration coefficients.

J Dent Res 2008 87: 1112-1116. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Methyl Methacrylate Activates the Gsta1 Promoter

N. Hattori, T. Suzuki, S. Jinno, H. Okeya, A. Ishikawa, C. Kondo, T. Hayashi, M. Ito, T. Kanamori, T. Kawai, and T. Noguchi
Methyl methacrylate increases Gsta1 transcription through anti-oxidant-responsive-element-mediated promoter activation.

J Dent Res 2008 87: 1117-1121. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Light-transmitting Ability of Marketed Fiber Posts

C. Goracci, G. Corciolani, A. Vichi, and M. Ferrari
The aim of this study was to verify whether the light-transmitting ability of marketed fiber posts reflected the manufacturers’ claims for translucency.

J Dent Res 2008 87: 1122-1126. [Abstract] [Full Text] [Figures Only] [PDF]  

Damage Maps of Veneered Zirconia under Simulated Mastication

J.-W. Kim, J.-H. Kim, M.N. Janal, and Y. Zhang
Deep-penetrating occlusal surface partial cone fracture is the predominant fracture mode of porcelain veneers.

J Dent Res 2008 87: 1127-1132. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

Enamel Proteases Reduce Amelogenin-Apatite Binding

Z. Sun, D. Fan, Y. Fan, C. Du, and J. Moradian-Oldak
Stepwise processing of amelogenin by MMP-20 and then KLK4 reduces amelogenin-apatite interactions.

J Dent Res 2008 87: 1133-1137. [Abstract] [Full Text] [Figures Only] [PDF]  

Vascularization of Engineered Teeth

A. Nait Lechguer, S. Kuchler-Bopp, B. Hu, Y. Haïkel, and H. Lesot
In implanted re-associations, newly formed blood vessels originate from the host, allowing for their survival, and affording conditions for organ growth, mineralization, and enamel secretion.

J Dent Res 2008 87: 1138-1143. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Effects of VEGF and FGF2 on the Revascularization of Severed Human Dental Pulps

E.M. Mullane, Z. Dong, C.M. Sedgley, J.C.-C. Hu, T.M. Botero, G.R. Holland, and J.E. Nör
rhVEGF₁₆₅ enhanced neovascularization of severed human dental pulps, and topical application of an angiogenic factor prior to replantation might be beneficial for the treatment of avulsed teeth.

J Dent Res 2008 87: 1144-1148. [Abstract] [Full Text] [Figures Only] [PDF]  

Time-dependent Activation of ERK1/2 in Nerve Terminals of the Dentin-Pulp Complex following Bradykinin Treatment

Y. Korkmaz, W. Bloch, K. Schneider, S. Zimmer, K. Addicks, and W.H.-M. Raab
Bradykinin induces phosphorylation-mediated local activation of ERK1/2 in nerve terminals modulating nociception in the dentin-pulp complex.

J Dent Res 2008 87: 1149-1154. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

iNOS -derived Nitric Oxide Modulates Infection-stimulated Bone Loss

S.Y. Fukada, T.A. Silva, I.F. Saconato, G.P. Garlet, M.J. Ávila-Campos, J.S. Silva, and F.Q. Cunha
Nitric oxide deficiency is associated with an imbalance of bone-resorption-modulating factors, leading to severe infection-stimulated bone loss.

J Dent Res 2008 87: 1155-1159. [Abstract] [Full Text] [Figures Only] [PDF]  

Regulation of CXCL9/10/11 in Oral Keratinocytes and Fibroblasts

K. Ohta, H. Shigeishi, M. Taki, H. Nishi, K. Higashikawa, M. Takechi, and N. Kamata
IFN-, TNF-, and IL-4 appear cooperatively to regulate CXCR3-agonistic chemokines in oral keratinocytes and fibroblasts in T-cell-mediated oral inflammation sites.

J Dent Res 2008 87: 1160-1165. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Effect of PTK/ZK on the Angiogenic Switch in Head and Neck Tumors

M. Miyazawa, Z. Dong, Z. Zhang, K.G. Neiva, M.M. Cordeiro, D.T. Oliveira, and J.E. Nör
PTK/ZK blocks downstream targets of VEGF signaling in endothelial cells, suggesting that PTK/ZK may inhibit the angiogenic switch in head and neck tumors.

J Dent Res 2008 87: 1166-1171. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Clinical:

Phenotypic Heterogeneity of Streptococcus mutans in Dentin

S. Rupf, M. Hannig, K. Breitung, W. Schellenberger, K. Eschrich, T. Remmerbach, and S. Kneist
The authors confirm the substantial heterogeneity of S. mutans and prove that S. mutans can survive under adverse conditions for a limited period of time.

J Dent Res 2008 87: 1172-1176. [Abstract] [Full Text] [Figures Only] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.