D E P A R T M E N T S:

GUEST EDITORIAL:

Facing the Future: the NIDCR Celebrates its 60th Anniversary

A. Isabel Garcia and Lawrence A. Tabak
The authors—Deputy Director and Director of the NIDCR, respectively—reflect on the 60-year history of the Institute and its role in the future of dental and craniofacial research.

J Dent Res 2008 87: 509. [Full Text] [PDF]  

SPEECH:

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B.H. Clarkson
This is the text of the President-elect’s speech delivered during the Opening Ceremonies of the 37th Annual Meeting of the American Association for Dental Research, April 2, 2008, Dallas, Texas.

J Dent Res 2008 87: 510. [Full Text] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Implications for Creutzfeldt-Jakob Disease (CJD) in Dentistry: a Review of Current Knowledge

J.T. Walker, J. Dickinson, J.M. Sutton, P.D. Marsh, and N.D.H. Raven
This review explores current understanding of the risks of variant Creutzfeldt-Jakob disease transmission via dental practice, and whether they merit the rigorous enforcement of improved standards of instrument cleaning and decontamination.

J Dent Res 2008 87: 511-519. [Abstract] [Full Text] [PDF]  

SCPP Gene Evolution and the Dental Mineralization Continuum

K. Kawasaki and K.M. Weiss
The authors review comparative analyses of mineralized dental tissues, with particular emphasis on the use of secretory calcium-binding phosphoproteins, within and between tetrapods and teleosts.

J Dent Res 2008 87: 520-531. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Surface Analysis of Etched Molar Enamel by Gas Adsorption

M.F. Orellana, A.E. Nelson, J.P.R. Carey, G. Heo, D.G Boychuk, and P.W. Major
This study illustrates the possibilities that gas adsorption analysis offers to researchers in different dental disciplines.

J Dent Res 2008 87: 532-536. [Abstract] [Full Text] [Figures Only] [PDF]  

N-acetyl Cysteine Protects Pulp Cells from Resin Toxins in vivo

A. Paranjpe, E.C. Sung, N.A. Cacalano, W.R. Hume, and A. Jewett
The addition of N-acetyl cysteine prior to or concomitant with the application of restorative materials may be beneficial for the health and safety of dental patients.

J Dent Res 2008 87: 537-541. [Abstract] [Full Text] [Figures Only] [PDF]  

Quantifying the Strength of a Resin-coated Dental Ceramic

O. Addison, P.M. Marquis, and G.J.P. Fleming
Resin cement coating significantly increased the mean strength attributed to a resin-ceramic hybrid layer that is sensitive to surface texture.

J Dent Res 2008 87: 542-547. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinically Relevant Cell Sources for TMJ Disc Engineering

D.E. Johns, M.E. Wong, and K.A. Athanasiou
Costal chondrocytes can produce extracellular matrix that may function in TMJ disc replacement.

J Dent Res 2008 87: 548-552. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biological:

Antigen-presenting Cells in Human Radicular Granulomas

T. Kaneko, T. Okiji, R. Kaneko, J.E. Nör, and H. Suda
Dendritic cells in radicular granulomas are associated with local defense reactions as stronger antigen-presenting cells, as compared with macrophages.

J Dent Res 2008 87: 553-557. [Abstract] [Full Text] [Figures Only] [PDF]  

IL-1β and TNF- Regulate IL-6-type Cytokines in Gingival Fibroblasts

P. Palmqvist, P. Lundberg, I. Lundgren, L. Hänström, and U.H. Lerner
This is the first report of two cytokines in the IL-6 family, IL-11 and LIF, that can be expressed and positively regulated by IL-1β and TNF-, by a mechanism involving MAP kinases, but not NF-B.

J Dent Res 2008 87: 558-563. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Mechanical Stress Induces Osteopontin via ATP/P2Y1 in Periodontal Cells

S. Wongkhantee, T. Yongchaitrakul, and P. Pavasant
This is the first report showing that adenosine triphosphate induces osteopontin expression.

J Dent Res 2008 87: 564-568. [Abstract] [Full Text] [Figures Only] [PDF]  

Enhanced Enamel Remineralization under Acidic Conditions in vitro

H. Yamazaki and H.C. Margolis
The authors describe an acidic remineralizing solution that can significantly accelerate the rate, depth of penetration, and extent of remineralization of artificial incipient lesions in human enamel.

J Dent Res 2008 87: 569-574. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Clinical:

PTCH1 and SMO Gene Alterations in Keratocystic Odontogenic Tumors

L.-S. Sun, X.-F. Li, and T.-J. Li
This is the first report of the screening of SMO alterations in keratocystic odontogenic tumors.

J Dent Res 2008 87: 575-579. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Ectopic Maxillary Canines: Segregation Analysis and a Twin Study

S. Camilleri, C.M. Lewis, and F. McDonald
This study addressed the hypothesis that genetic factors play a role in the etiology of ectopic maxillary canines.

J Dent Res 2008 87: 580-583. [Abstract] [Full Text] [Figures Only] [PDF]  

The Seven-year Outcome of an Early Orthodontic Treatment Strategy

H. Kerosuo, M. Väkiparta, M. Nyström, and K. Heikinheimo
An early treatment strategy may considerably reduce the need for orthodontic treatment in public health care with limited specialist resources.

J Dent Res 2008 87: 584-588. [Abstract] [Full Text] [Figures Only] [PDF]  

Staphylococcus aureus and Other Bacteria in Untreated Periodontitis

B. Zinsli Fritschi, A. Albert-Kiszely, and G.R. Persson
P. intermedia, S. aureus, and S. mutans are robust in diagnosing sites in people with aggressive periodontitis, and S. aureus, S. sanguinis, and T. forsythia differentiate smoking status.

J Dent Res 2008 87: 589-593. [Abstract] [Full Text] [Figures Only] [PDF]  

Professional Oral Health Care Reduces the Number of Oropharyngeal Bacteria

A. Ishikawa, T. Yoneyama, K. Hirota, Y. Miyake, and K. Miyatake
Weekly professional mechanical cleaning of the oral cavity can be an important strategy to prevent aspiration pneumonia in the dependent elderly.

J Dent Res 2008 87: 594-598. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

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